Charlotte Fribbens, Isaac Garcia-Murillas, Matthew Beaney, Sarah Hrebien, Karen Howarth, Michael Epstein, Nitzan Rosenfeld, Alistair Ring, Stephen Johnston and Nicholas C. Turner

Tracking evolution of aromatase inhibitor resistance with circulating tumor DNA in metastatic breast cancer
ASCO2017, Chicago
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Besse B, Remon J, Lacroix L, Mezquita L, Jovelet C, Howarth K, Plagnol V, Morris C, Nicotra C, Pannet C, Green E, Soria JC.

Evaluation of liquid biopsies for molecular profiling in untreated advanced non-small cell lung cancer (NSCLC) patients
ASCO2017, Chicago
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Remon J, Besse B, Lacroix L, Mezquita L, Jovelet C, Howarth K, Plagnol V, Morris C, Nicotra C, Pannet C, Green E, Soria JC

Evaluation of liquid biopsies for molecular profiling in advanced non-small cell lung cancer (NSCLC) patients in the relapse treatment setting
ASCO2017, Chicago
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Nicolas M Guibert, Cloud Paweletz, Yuebi Hu, Nora Feeney, Vincent Plagnol, Valerie Poole, Greg Jones, Geoffrey Oxnard

Early detection of competing resistance mutations using plasma next-generation sequencing in patients with EGFR-mutant NSCLC treated with osimertinib
ASCO2017, Chicago
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Penelope A. Bradbury, Keyue Ding, Peter M. Ellis, Lesley Seymour, Frank De Kievit, Greg Jones, Clive Morris, Emma, Green, Glenwood D. Goss, Ming Sound Tsao, Frances A. Shepherd

Evaluation of stored liquid biopsies for molecular profiling in non-small cell lung cancer (NSCLC) patients
ASCO2017, Chicago
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Catenacci DVT, Green E, Epstein M, Jones G, Morris C, O’Day E, Lomnicki S, Maranto M, Karrison T, Kindler

Molecular profiling of advanced pancreatic cancer (PC) patients from a phase I/II study using circulating tumor DNA
ASCO2017, Chicago
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J. Remon, C. Caramella, C. Jovelet, L. Lacroix, A. Lawson, S. Smalley, K. Howarth, D. Gale, E. Green, V. Plagnol, N. Rosenfeld, D. Planchard, M. V. Bluthgen, A. Gazzah, C. Pannet, C. Nicotra, E. Auclin, J. C. Soria and B. Besse

Osimertinib benefit in EGFR-mutant NSCLC patients with T790M-mutation detected by circulating tumour DNA.
Annals of Oncology, April 2017
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Jonathan C. M. Wan, Charles Massie, Javier Garcia-Corbacho, Florent Mouliere, James D. Brenton, Carlos Caldas, Simon Pacey, Richard Baird and Nitzan Rosenfeld

Liquid biopsies come of age: towards implementation of circulating tumour DNA
Nature Reviews Cancer, April 2017
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Isaac Garcia-Murillas, Matthew Beaney, Michael Epstein, Karen Howarth, Andrew Lawson, Sarah Hrebien, Emma Green, Nitzan Rosenfeld and Nicholas C. Turner

Comparison of enhanced Tagged-Amplicon Sequencing and digital PCR for circulating tumor DNA analysis in advanced breast cancer
AACR, Washington USA, April 2017
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Christine A. Parkinson, Davina Gale, Anna Piskorz, Heather Biggs, Charlotte Hodgkin, Helen Addley, Sue Freeman, Penelope Moyle, Evis Sala, Karen Sayal, Karen Hosking, Ioannis Gounaris, Mercedes Jimenez-Linan, Helena M. Earl, Wendi Qian, Nitzan Rosenfeld, James Brenton

Exploratory Analysis of TP53 Mutations in Circulating Tumour DNA as Biomarkers of Treatment Response for Patients with Relapsed High-Grade Serous Ovarian Carcinoma: A Retrospective Study
PLOS Medicine, 20 December, 2016 - Research was conducted through CRUK, not Inivata.
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Remon J, Caramella C, Jovelet C, Lacroix L, Lawson A, Smalley S, Howarth K, Gale D, Rosenfeld N, Green E, Plagnol V, Planchard D, Bluthgen MV, Gazzah A, Pannet C, Nicotra C, Soria JC, Besse B

Osimertinib benefit in ctDNA T790Mpositive, EGFR-mutant NSCLC patients
WCLC, Vienna, December 2016
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Tim Forshew, Andrew Lawson, Sarah Smalley, Vincent Plagnol, John Calaway, Shannon Blais, Karen Howarth, Greg Jones, Michelle Pugh, Mikidache Madi, Bradley Durham, Esther Musgrave-Brown, Samuel Woodhouse, Nitzan Rosenfeld, Davina Gale, Emma Green and James Clark

Analytical performance and validation of an InVision® circulating tumour DNA sequencing assay across two laboratories
WCLC, Vienna, December 2016
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Karen Howarth, John Calaway, Sarah Smalley, Shannon Blais, Andrew Lawson, Greg Jones, Davina Gale, Michelle Pugh, Mikidache Madi, Bradley Durham, Esther Musgrave-Brown, Samuel Woodhouse, Tim Forshew, Emma Green, Vincent Plagnol, Nitzan Rosenfeld and James Clark

Analytical performance and validation of an enhanced TAm-Seq™ circulating tumour DNA sequencing assay across two laboratories
NCRI 2016, Liverpool, UK, November 2016
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Remon J, Soria JC, Planchard D, Jovelet C, Pannet C, Lacroix L, Gazzah A, Lawson A, Smalley S, Howarth K, Gale D, Green E, Plagnol V, Rosenfeld N, Oulassen K, Besse B

Liquid biopsies for molecular profiling of mutations in non-small cell lung cancer (NSCLC) patients lacking tissue samples
MAP 2016, London, UK, September 2016
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Remon J, Soria JC, Lacroix L, Howarth K, Lawson A, Smalley S, Gale D, Plagnol V, Green E, Rosenfeld N, Planchard D, Jovelet C, Pannet C, Besse B

Evaluation of liquid biopsies for molecular profiling and monitoring in advanced non-small cell lung cancer (NSCLC) patients
ASCO 2016, Chicago, US, June 2016
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Remon J, Soria JC, Planchard D, Jovelet C, Pannet C, Lacroix L, Gazzah A, Lawson A, Smalley S, Howarth K, Gale D, Green E, Plagnol V, Rosenfeld N, Olaussen K, Chaput N, Besse B

Liquid biopsies for molecular profiling of mutations in non-small cell lung cancer (NSCLC) patients lacking tissue samples
AACR 2016, New Orleans, US, April 2016
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Davina Gale, Vincent Plagnol, Andrew Lawson, Michelle Pugh, Sarah Smalley, Karen Howarth, Mikidache Madi, Bradley Durham, Vasudev Kumanduri, Kitty Lo, Peter Dimitrov, Jordi Remon, Benjamin Besse, James Clark, Emma Green, Nitzan Rosenfeld, Tim Forshew

Analytical performance and validation of an enhanced TAm-Seq™ circulating tumor DNA sequencing assay
AACR Annual Meeting, New Orleans, US, April 2016
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Davina Gale, Jordi Remon, Andrew RJ Lawson, Sarah Smalley, Esperanza Perez, Karen D Howarth, Michelle Pugh, Abdelaziz Fahem, Tim Forshew, Amanda Bettison, John Beeler, Ludovic Lacroix, Emma Green, Michael Stocum, Vincent Plagnol, Benjamin Besse, Nitzan Rosenfeld

Assessment of clinical applications of circulating tumour DNA in lung cancer using an enhanced TAm-Seq™ platform
International Association for the Study of Lung Cancer Conference, Denver, September 2015
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Sarah Smalley, Davina Gale, Andrew RJ Lawson, Jordi Remon, Esperanza Perez, Michelle Pugh, Karen D Howarth, Mehdi Touat, Jean-Charles Soria, Antoine Hollebecque, Emma Green, Benjamin Besse, Tim Forshew, Vincent Plagnol, Ludovic Lacroix, Nitzan Rosenfeld

Assessing the clinical applications of ctDNA in patients with advanced stage metastatic cancer using our enhanced TAm-Seq™platform
Molecular Targets and Cancer Therapeutics, Boston, November 2015
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Murtaza M, Dawson SJ, Tsui DW, Gale D, Forshew T, Piskorz AM, Parkinson C, Chin SF, Kingsbury Z, Wong AS, Marass F, Humphray S, Hadfield J, Bentley D, Chin TM, Brenton JD, Caldas C, Rosenfeld N.

Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA
Nature. 2013 May 2;497(7447):108-12. doi: 10.1038/nature12065. Epub 2013 Apr 7. PubMed PMID: 23563269.
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Dawson SJ, Tsui DW, Murtaza M, Biggs H, Rueda OM, Chin SF, Dunning MJ, Gale D, Forshew T, Mahler-Araujo B, Rajan S, Humphray S, Becq J, Halsall D, Wallis M, Bentley D, Caldas C, Rosenfeld N.

Analysis of circulating tumor DNA to monitor metastatic breast cancer
N Engl J Med. 2013 Mar 28;368(13):1199-209. doi: 10.1056/NEJMoa1213261. Epub 2013 Mar 13. PubMed PMID: 23484797.
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Forshew T, Murtaza M, Parkinson C, Gale D, Tsui DW, Kaper F, Dawson SJ, Piskorz AM, Jimenez-Linan M, Bentley D, Hadfield J, May AP, Caldas C, Brenton JD, Rosenfeld N.

Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA.
Sci Transl Med. 2012 May 30;4(136):136ra68. doi: 10.1126/scitranslmed.3003726. PubMed PMID: 22649089.
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