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A multi-tumor assay for the detection of residual disease and recurrence based on the InVision® liquid biopsy platform

The RaDaR assay is built on Inivata’s proven InVision® liquid biopsy platform technology. This next-generation sequencing platform incorporates built-in controls and error-correction for highly sensitive and specific variant detection.

RaDaR™ is a personalized assay that tracks a set of up to 48 tumor-specific variants in a patient using a liquid biopsy with exceptional sensitivity, allowing both detection of residual disease following curative intent or definitive treatment and early detection of relapse.

Initial applications for RaDaR™ will be in clinical research. The availability of an assay with a level of sensitivity that exceeds current fixed panel approaches will allow accurate patient selection for enriched clinical trial populations. This specific patient selection approach may allow for more focused clinical trials with faster recruitment rates. In addition, the ability to track therapeutic treatment success through accurate liquid biopsy will allow earlier visibility of drug efficacy.

Publications and Posters

Sensitive detection of ctDNA in early-stage non-small cell lung cancer patients with a personalized sequencing assay

Event name - AACR Virtual Annual Meeting II 2020

Katrin Heider, Davina Gale - PRESENTING AUTHOR, Andrea Ruiz-Valdepenas, Giovanni Marsico, Garima Sharma, Malcolm Perry, Peter Ellis, Robert Osborne, Karen Howarth, Tadd Lazarus, Viona Rundell, Jelena Belic, Jerome Wulff, Susan Harden, Doris M. Rassl, Robert C. Rintoul, Nitzan Rosenfeld Read More

Analytical development of the RaDaR™ assay, a highly sensitive and specific assay for the monitoring of minimal residual disease

Event name - AACR Virtual Annual Meeting II 2020

Giovanni Marsico, Garima Sharma, Malcolm Perry, Sophie Hackinger, Tim Forshew, Karen Howarth, Peter Ellis, Katrin Heider, Davina Gale, Robert C. Rintoul, Jamie Platt, Nitzan Rosenfeld, Robert Osborne Read More

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